abstract：:To study the symptoms of NSAID-associated gastroduodenal bleeding, 94 patients (median age 71 years, range 19-90), were included in a prospective, clinical trial where hematemesis or melena from gastroduodenal ulceration or haemorrhagic/erosive gastritis were the inclusion criteria. NSAID use within one month was stud...

journal_title：Scandinavian journal of rheumatology

authors： Aabakken L,Weberg R,Lygren I,Eidsvoll B,Stray N,Osnes M

更新日期：1991-01-01 00:00:00

abstract：:The risk of a disease flare-up and the side-effects experienced during the use of oral contraceptives (OCs) were studied in 85 female SLE patients, 18-44 years old, regularly attending two specialist rheumatological clinics. Thirty-one patients had used combined oral contraceptives (cOCs) during or after the onset of ...

journal_title：Scandinavian journal of rheumatology

authors： Julkunen HA

更新日期：1991-01-01 00:00:00

abstract：:We have recently shown that synoviocytes and extracellular matrices exhibit distinct patterns of carbohydrate expression. Their biological relevance is however not known. The purpose of the present study was to find out whether human synovial tissue would also show a specific receptor pattern for complex sugar molecul...

journal_title：Scandinavian journal of rheumatology

authors： Zschäbitz A,Gabius HJ,Stofft E,Reichel W

更新日期：1991-01-01 00:00:00

abstract：:Fc-receptors for IgG (Fc gamma R) are important triggers of effector function in macrophages. We have investigated the distribution of cells bearing Fc gamma R I, Fc gamma R II, and Fc gamma R III in 14 synovia and 3 nodules from rheumatoid arthritis (RA) patients, using monoclonal antibodies on serial cryostat sectio...

journal_title：Scandinavian journal of rheumatology

authors： Bröker BM,Edwards JC,Fanger MW,Lydyard PM

更新日期：1990-01-01 00:00:00

abstract：:The effects of rheumatoid arthritis on locomotion status were assessed in an epidemiologically representative Swedish population sample. In a steady community of 12,707 inhabitants, 82 patients were found fulfilling ARA criteria 5-8 (Rome 1961). Prevalence was 0.51% for men, 0.78 for women and 0.65 in the overall popu...

journal_title：Scandinavian journal of rheumatology

authors： Jonsson B,Larsson SE

更新日期：1990-01-01 00:00:00

abstract：:Synovectomy of 20 wrist joints in 15 patients with juvenile chronic arthritis (JCA) was performed and results were evaluated 3 (0.5-5) years after surgery. The surgical procedure consisted of synovectomy of the radiocarpal joint, around the ulnar head and in all intercarpal joints. Resection of the ulnar head was not ...

journal_title：Scandinavian journal of rheumatology

authors： Hanff G,Sollerman C,Elborgh R,Pettersson H

更新日期：1990-01-01 00:00:00

abstract：:The subclass distribution of IgG and IgA plasma cells, and in IgG and IgA rheumatoid factor (RF) producing cells was studied in sections of synovial tissue from seropositive RA and various types of seronegative arthritis, including ankylosing spondylitis, psoriatic arthritis, and Reiter's syndrome. The study was perfo...

journal_title：Scandinavian journal of rheumatology

authors： Mellbye OJ,Vartdal F,Pahle J,Mollnes TE

更新日期：1990-01-01 00:00:00

abstract：:The immunoreactivity of the trophic peptide insulin-like growth factor I (IGF-I; somatomedin C) was mapped in nasal mucosa biopsies from three patients with Wegener's granulomatosis (WG) and one with idiopathic midline destructive disease (IMDD; idiopathic midline granuloma). Strongly increased IGF-I immuno-reactivity...

journal_title：Scandinavian journal of rheumatology

authors： Hansson HA,Petruson B,Petruson K

更新日期：1989-01-01 00:00:00

abstract：:Using the fluorescence polarization of 1.6-diphenyl-1, 3, 5-hexatriene, the membrane fluidity of lymphocytes obtained from rheumatoid arthritis patients was measured during 12 months of auranofin treatment. Significant differences in fluorescence polarization values were observed following auranofin treatment. The cor...

journal_title：Scandinavian journal of rheumatology

authors： Beccerica E,Piergiacomi G,Curatola G,Ferretti G

更新日期：1989-01-01 00:00:00

abstract：:Thirty-four patients with Sjögren's syndrome were retrospectively examined in order to evaluate longitudinal alterations in objective ocular disease parameters and their possible relation to systemic bromhexine treatment. Twenty-three patients (68%) were initially found to respond to peroral bromhexine treatment and w...

journal_title：Scandinavian journal of rheumatology

authors： Kriegbaum NJ,von Linstow M,Oxholm P,Prause JU

更新日期：1989-01-01 00:00:00

abstract：:The effects of piroxicam and D-penicillamine on T lymphocytes, NK cell activity and rheumatoid factor production as well as clinical parameters were studied in patients with rheumatoid arthritis. The level of total rheumatoid factor fell during treatment with D-penicillamine (p less than 0.02) and there was a positive...

journal_title：Scandinavian journal of rheumatology

authors： Thoen J,Helgetveit K,Førre O,Haile Y,Kåss E

更新日期：1988-01-01 00:00:00

abstract：:We have recently shown that synovial fibroblasts cultured from patients with reactive or rheumatoid arthritis exhibit increased autofluorescence when compared with controls. Morphological studies suggested that this increase was related to the anomalous structure of mitochondria in cells cultured from rheumatoid or no...

journal_title：Scandinavian journal of rheumatology

authors： Pulkki KJ,Eerola ET,Saario RM,Toivanen A,Vuorio EI

更新日期：1988-01-01 00:00:00

abstract：:Immobilization of a rabbit leg in extension results in the early development of an aseptic inflammation, synovial effusion and stiffening, and subsequent osteoarthritis of the knee. To study the pathogenesis of this experimental osteoarthritis, the hydrostatic pressures were measured in the knee, and distal metaphysis...

journal_title：Scandinavian journal of rheumatology

authors： Kallio PE,Michelsson JE,Björkenheim JM

更新日期：1988-01-01 00:00:00

abstract：:Radiographs of hands and feet were obtained from 125 consecutive patients with rheumatoid arthritis (RA) and the degree of destruction was assessed numerically on a 200-point scale using Larsen's standard radiographs as reference. The method is shown to possess a satisfactory degree of reproducibility. In 96 of these ...

journal_title：Scandinavian journal of rheumatology

authors： Wollheim FA,Pettersson H,Saxne T,Sjöblom KG

更新日期：1988-01-01 00:00:00

abstract：:The initial evaluation of 25 patients suspected of suffering from Sjögren's syndrome (SS) disclosed that sialopenia and glandular atrophy without focal sialo-adenitis was the second most common cause, after SS itself, of patient complaints. This emphasizes the importance of conclusive diagnostic criteria to prevent ov...

journal_title：Scandinavian journal of rheumatology

authors： Malmström MJ,Segerberg-Konttinen M,Tuominen TS,Hietanen JH,Wolf JE,Sane JI,Konttinen YT

更新日期：1988-01-01 00:00:00

abstract：:The prevalence of rheumatoid arthritis in 1,287 persons living in densely populated areas and 1, 287 persons living in thinly populated areas, matched as to sex, age, occupation and geographical area, was compared. The patient material was obtained in an epidemiological survey of rheumatoid arthritis (ARA definition) ...

journal_title：Scandinavian journal of rheumatology

authors： Hellgren L

更新日期：1987-01-01 00:00:00

abstract：:The effect of osmium tetroxide, which is used in treatment of rheumatoid arthritis, was histologically and electronmicroscopically examined in the normal synovial membrane of the rabbit. The animals were albino rabbits, and they were 20 altogether. 0.3 ml. of 1% OsO(4) solution was injected, i.a., in the right knee. T...

journal_title：Scandinavian journal of rheumatology

authors： Möttönen M,Pantio M,Nevalainen T

更新日期：1987-01-01 00:00:00

abstract：:Thirty cases of unilateral or bilateral atlanto-axial arthritis are described. They were found among 606 RA patients. According to the degree of involvement, the 30 cases were divided into four groups: A. 16 cases. B. 5 cases. C. 7 cases. D. 2 cases. In two patients the atlanto-axial arthritis was the primary lesion. ...

journal_title：Scandinavian journal of rheumatology

authors： Kerckhove HV

更新日期：1987-01-01 00:00:00

abstract：:In the general population of 39,418 persons within areas in the counties of Norrbotten (BD), Jämtland (Z), Skaraborg (R), Kristianstad west coast (LV), and Kristianstad east coast (L) in Sweden all the inhabitants over the age of seven (in Norrbotten over the age of 14) were investigated for the total number of cases ...

journal_title：Scandinavian journal of rheumatology

authors： Hellgren L

更新日期：1987-01-01 00:00:00

abstract：:In 9 patients with active rheumatoid arthritis we studied gastrointestinal blood loss during well tolerated therapy with the non-steroidal anti-inflammatory drug naproxen, 500 mg twice daily. The mean gastrointestinal blood loss, assessed with reinfused autologous 51Cr-labelled erythrocytes, was 1.4 +/- 0.6 ml/day (me...

journal_title：Scandinavian journal of rheumatology

authors： van den Ouweland FA,Corstens FH,van de Putte LB,Gribnau FW

更新日期：1987-01-01 00:00:00

abstract：:We studied HLA antigens in 105 unrelated American Caucasian patients with rheumatoid arthritis (RA), 70 of them with familial disease. HLA-DR4 was observed in 71% of familial RA, 63% of non-familial RA, and 27% of normal controls, confirming the already well-established association between HLA-DR4 and both familial an...

journal_title：Scandinavian journal of rheumatology

authors： Khan MA,Wolfe F,Kleinheksel SM,Molta C

更新日期：1987-01-01 00:00:00

abstract：:The degrees of anaemia and microcytosis in 100 patients with juvenile chronic arthritis (JCA) were analysed according to the pattern of disease and its activity. Microcytosis was common (40% of patients had a mean corpuscular volume (MCV) of less than 75 fl), sometimes severe (MCV less than 65 fl in 14 patients), and ...

journal_title：Scandinavian journal of rheumatology

authors： Harvey AR,Pippard MJ,Ansell BM

更新日期：1987-01-01 00:00:00

abstract：:Radiological examinations of the temporomandibular joints are not so often performed in patients with rheumatoid arthritis (RA). However, greater abnormalities of the mandibular head and neck may be evaluated at cervical radiography. With a new method, where the perpendicular distance from the palato-occipital line to...

journal_title：Scandinavian journal of rheumatology

authors： Redlund-Johnell I

更新日期：1987-01-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay was used to detect antiglobulins (rheumatoid factors, RF) of various classes in 33 patients with recently diagnosed rheumatoid arthritis and to follow their progress with 3-monthly checks for 1 year. For RF, IgA-RF and IgM-RF showed greater sensitivity than the latex test, either o...

journal_title：Scandinavian journal of rheumatology

authors： March RE,Kirwan JR,Reeback JS,Holborow EJ

更新日期：1987-01-01 00:00:00

abstract：:Shoulder muscle performance was tested in 8 working ankylosing spondylitis (AS) patients and compared with 10 healthy male referents. The AS patients were all in a non-active state and had no shoulder symptoms. Electromyographic fatigue development in the descending part of the trapezius muscle was significantly faste...

journal_title：Scandinavian journal of rheumatology

authors： Hagberg M,Hagner IM,Bjelle A

更新日期：1987-01-01 00:00:00

abstract：:Nine patients with active classical rheumatoid arthritis (ARA criteria) were studied with reference to circadian variation of immunological and clinical parameters. Complement-mediated solubilization (CMS) of immune complexes (IC) and the level of circulating IC were found to be inversely related with low CMS and incr...

journal_title：Scandinavian journal of rheumatology

authors： Petersen I,Baatrup G,Brandslund I,Teisner B,Rasmussen GG,Svehag SE

更新日期：1986-01-01 00:00:00

abstract：:Twenty-four female and 4 male patients, all fulfilling the Copenhagen criteria for primary Sjögren's syndrome (primary SS), were treated for 8 weeks with evening primrose oil (Efamol). Efamol is a seed oil which consists primarily of the n-6 essential fatty acids (EFA): cis-linoleic acid and gammalinolenic acid (GLA)....

journal_title：Scandinavian journal of rheumatology

authors： Oxholm P,Manthorpe R,Prause JU,Horrobin D

更新日期：1986-01-01 00:00:00

abstract：:The IgG subclass distribution of anti-RNP antibodies was determined in sera from 34 patients. The antibodies were mainly of the complement-fixing IgG1 subclass with minor contributions of IgG3 and IgG4 antibodies. Selected sera contained IgG2 (non-complement fixing) anti-RNP antibodies and may possibly identify a subg...

journal_title：Scandinavian journal of rheumatology

authors： Hammarström L,Heigl Z,Smith CI

更新日期：1986-01-01 00:00:00

abstract：:An impairment of the renal function was observed in three patients who received azapropazone for various rheumatic disorders with simultaneous hyperuricaemia. A distinct increase in serum creatinine occurred in all patients. In one case the renal biopsy suggested a hypersensitivity reaction with a consequent acute tub...

journal_title：Scandinavian journal of rheumatology

authors： Sipilä R,Skrifvars B,Törnroth T

更新日期：1986-01-01 00:00:00

abstract：:'Arthroscopic volume' and resorption of normal saline was measured in 35 young males during routine arthroscopic examination. The average mean volume of the knee joint cavity was 103.4 ml and this volume was observed to correlate with the midpatellar circumference of the knee and the height of the patients. Mean resor...

journal_title：Scandinavian journal of rheumatology

authors： Visuri T,Kiviluoto O

更新日期：1986-01-01 00:00:00

abstract：:The lupus anticoagulant (LAC) is associated with the occurrence of thromboembolic complications. Assuming that thrombosis may underlie manifestations of the central nervous system (CNS) in patients with systemic lupus erythematosus (SLE), we studied 20 patients with SLE and CNS manifestations for the presence of LAC. ...

journal_title：Scandinavian journal of rheumatology

authors： Derksen RH,Bouma BN,Kater L

更新日期：1986-01-01 00:00:00

abstract：:The aetiology of ankylosing spondylitis (AS) may involve certain enterobacteria. It is therefore interesting that serum polymeric IgA, a precursor of secretory IgA, was statistically elevated in active AS (n = 35) and that levels were comparable to those found in yersiniosis (n = 12); this might indicate antigenic sti...

journal_title：Scandinavian journal of rheumatology

authors： van Bohemen CG,Nabbe AJ,Goei The HS,Mazurkiewicz ES,van der Linden S,Zanen HC

更新日期：1986-01-01 00:00:00

abstract：:SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) is a new sulfhydryl compound having a relatively similar chemical structure to Tiopronin and D-penicillamine. An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and wit...

journal_title：Scandinavian journal of rheumatology

authors： Ishikawa K,Sakaguchi M

更新日期：1986-01-01 00:00:00

abstract：:A technique for assessing the overall consequences of disease is introduced, comprising a Swedish version of a behaviour-based measure, the Sickness Impact Profile (SIP). Measurement characteristics of the profile are defined in an epidemiological study of 147 women with rheumatic disorders. The drop-out rate was 7.5%...

journal_title：Scandinavian journal of rheumatology

authors： Sullivan M,Ahlmén M,Archenholtz B,Svensson G

更新日期：1986-01-01 00:00:00

abstract：:In studies on 779 fresh, unselected ANA+ sera, 50 (6.4%) were found to have anti-dsDNA antibodies, by using CIP (C. luciliae immunoperoxidase), and 84% of the 50 patients met the criteria for definite SLE. After freezing 36 of these sera for 13 +/- 1 months, only 52.8% were again positive by CIP. Using CIF (C. lucilia...

journal_title：Scandinavian journal of rheumatology

authors： Lee TK,Rothberger H

更新日期：1985-01-01 00:00:00

abstract：:Thirty-eight patients (age 27-73 years) with unilateral hip pain, restricted movement of the hip joint and radiologically no or only slight osteoarthrosis were studied in a double-blind controlled clinical trial. Twenty-one patients received active treatment with hip joint distension arthrography and 17 received place...

journal_title：Scandinavian journal of rheumatology

authors： Høilund-Carlsen PF,Meinicke J,Christiansen B,Karle AK,Stage P,Uhrenholdt A

更新日期：1985-01-01 00:00:00

abstract：:In a prospective study, the clinical features and synovial histopathology of 78 patients with joint disease were compared. Nineteen patients had early rheumatoid disease, 19 chronic rheumatoid, 17 chondrocalcinosis or osteoarthritis, 10 persistent monoarthritis and 14 other miscellaneous arthropathies. After semiquant...

journal_title：Scandinavian journal of rheumatology

authors： Gallagher PJ,Blake DR,Lever JV

更新日期：1985-01-01 00:00:00

abstract：:Eight patients with a radiological diagnosis of Osteitis condensans ilii (OCI) had clinical features similar to those of 8 patients with sacro-iliitis (SI). The X-ray appearances may be very difficult to differentiate on standard films and discrimination between the two conditions has to be made from a combination of ...

journal_title：Scandinavian journal of rheumatology

authors： Withrington RH,Sturge RA,Mitchell N

更新日期：1985-01-01 00:00:00

abstract：:Lysozyme (LZM) concentrations in synovial fluid were determined in patients with seropositive and seronegative rheumatoid arthritis (RA) and in patients whose arthritic exudates had been caused by Reiter's disease, a Yersinia enterocolitica infection, osteoarthritis, or trauma. Patients with rheumatoid disease had sig...

journal_title：Scandinavian journal of rheumatology

authors： Klockars M,Pettersson T

更新日期：1985-01-01 00:00:00

abstract：:Corneal chrysiasis is a common consequence of parenteral chrysotherapy in patients affected by rheumatoid arthritis. Concerning the factors and conditions that could be determinant for the gold accumulation in the cornea, there are contradictory opinions. Total or weekly gold dose and its accumulation quota, and the f...

journal_title：Scandinavian journal of rheumatology

authors： Mathieu A,Pala R,Carta S,Orzalesi N,Balestrieri A

更新日期：1985-01-01 00:00:00